A new paper out!
Sugammadex (SGM) is the first cyclodextrin (CD)-based selective relaxant binding agent. We investigated its ability to capture natural aminosteroid phytotoxins, and assessed its potential as an antidote for intoxication.
SGM significantly increased cell survival and reduced Solasodine (the toxic alkaloid chosen as model compound) toxicity in mHippoE-14 mouse hippocampal embryonic cells, supporting the hypothesis that SGM could act as an antidote to SS’s toxic effects.
Special thanks for the fantastic teamwork:
Eszter Kalydi – Semmelweis University
Fanni Sebák, Éva Moussong József Kardos, Andrea Bodor Szabolcs Béni – Eötvös Loránd University
Béla Fiser – University of Miskolc
Babak Minofar – University of Lodz
Milo Malanga PhD – CarboHyde
